Tuesday, November 19, 2013

NO, Not the fries!



Fries are my weakness, just by reading this article and no matter what scientists say, I just want to go out and get fries. Well the FDA is warning people to cut down on acrylamide.   This chemical is linked to cancer, acrylamide can form in plant-based, starchy foods when cooked at high-temperatures like baking or frying. Foods that contain acrylamide include french fries, coffee, crackers, toasted breads and dried fruits. I know almost everything causes cancer but why does it have to be french fries and coffee. The acrylamide chemical is created from sugars and an amino acid that is found in food,  but does not form in dairy, meat or fish products. Research on this chemical is relatively new, but it has been linked to higher rates of cancer in animals so it is thought to be a carcinogen for humans as well.

Steps to reduce acrylamide:
Stop consumption of one or two foods high in acrylamide
Boil or steams foods, this does not form acrylamide
Do not overcook or over crisp when frying
Cook potatoes till golden yellow not brown
Do not store potatoes in the refrigerator (the refrigerator increases the amount of acrylamide)
Bread should be toasted to light brown, very brown areas should not be eaten
Eat plenty of fruits, vegetables, whole grains, and lean meats

Ok, so these steps are not so bad, but would you put down the fries? Would you go on this craze and do what they say or just continue to eat the same?

Here is the article if you would like to read it:

Wednesday, November 13, 2013

Milk that can kill human stomach cancer cells?

A research team in Taiwan indicates that peptide fragment derived from cow’s milk can kill human stomach cancer cells. Three peptide fragments derived from lactoferricin B which is a peptide in milk were evaluated, only one of these fragments, LFcinB25 reduced the survival of human Gastric Adenocarcinoma cells. After an hour, LFcinB25 migrated to the cell membrane of the Gastric Adenocarcinoma cells, within 24 hours the cancer cells had shrunk in size and lost the ability to adhere to surfaces. This study also suggested Beclin-1 may enhance LFcinB25 cytotoxic action. Beclin-1 plays a central role in tumor growth. This study found that cleaved beclin-1 increase over time after LFcinB25 exposure. This will be used to potentially treat gastric cancer.

Should this study be further explored? Or should this be shut down? There are many studies out there to find a treatment, but what do you think is important in a good study?

Here is the article if you like to read it:


Tuesday, November 5, 2013

New Theory for Cancer Development

A team at Harvard Medical School has come up with a way to understand the aneuplodiy patterns in tumors and how to predict which genes affect chromosomes that are most likely to be cancer suppressors or promoters. This study proposed that aneuplodiy is a driver of cancer not a result of cancer.

Over the years, cancer research has focused on mutations that change the DNA and promotes cancer. The role of aneuplodiy has not been unstudied. This study predicts that the aneuploidy has a significant role in cancer. This prediction is because the missing or extra chromosomes likely affect genes that are involved in tumor related process.

This study was tested by a developed computer program called TUSON (Tumor Suppressor and Oncogene). This program analyzes the genome sequence from more than 8,200 pairs of cancerous and normal tissue samples. This generates a list of suspected oncogenes and tumor suppressor genes based on the mutation pattern. These also created a list of many more potential cancer drivers. From these lists, they discovered that the number of tumor suppressor genes or oncogenes in a chromosome correlated with how often the whole chromosome or part of the chromosome was deleted or duplicated in the cancer.

These concluded that aneuplody is a driver of cancer not a consequence of cancer. Since this has been discovered, studies can now be done to figure out how mutations, rearrangements and changes in expression weigh into cancer. They plan to gather experimental evidence to support this mathematical finding. Should they continue and explore this conclusion? Would this help researchers find a cure?

Here is the article if you would like to read it: